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• 12/2025 Congrats to Xiaofan for successfully passing the pre-qualification exam! Well done!
• 11/2025 Ya-Mei's work on androgen receptor activity and immunity was published in Cancer Research Communications. Congratulations!
• 07/2025 Ya-Mei's work on enzalutamide extreme non-response in prostate cancer was published in npj Precision Oncology. Congratulations!
• 06/2025 Canping received a Frohnmayer Hicks Sciarretta Cancer Research Scholar award, which supports outstanding PhD students working in cancer research. Congratulations!
• 05/2025 Xinxing and Faming's paper was accepted by Cell Genomics. We have developed a unified framework, OmicsTweezer, for the deconvolution of bulk RNA-seq, proteomics, and low-resolution spatial omics. Congratulations!
• 12/2024 A Multiple PI NCI R01 is funded through the collaboration with the City of Hope!
• 12/2024 Yi passed his PhD qualifying exam! Congratulations!
• 10/2024 Tao and Xiaofan's paper was accepted to Immunity & Ageing. We have developed a tool called PhAre to predict physiological ages from single-cell and bulk RNA-seq PBMCs.
• 07/2024 Welcome to the four new postdocs joining our lab, each bringing their expertise in mathematics, medicine, electrical engineering and electronic information!
• 06/2024 Our work is highlighted by OHSU Research Week!
• 06/2024 Canping passed his PhD qualifying exam! Congratulations!
• 03/2024 We received a Prostate Cancer Data Science Award!
• 01/2024 Honored to receive Silver Family Foundation Faculty Excellence and Innovation Award!
• 10/2023 A pilot project from the Knight Quantitative Oncology Program has been awarded. Cheers!
• 07/2023 Tao's machine-learning-based tool PENCIL for identifying phenotypic subpopulations from single-cell data was accepted to Nature Machine Intelligence. Congratulations!
• 03/2023 Our first-year PhD student Canping Chen published his paper in Leukemia. Congratulations!
• 03/2023 The paper with Dr. Alexey Danilov about CDK9 inhibition to circumvent resistance in lymphoma was accepted to Molecular Cancer. Cheers!
• 12/2022 In our BME department retreat, Xiyue, a first-year PhD student, was selected for an oral presentation. Moreover, Guan won the "Best Postdoctoral Fellow Paper of the Year" award. Congratulations!
• 11/2022 A collaborative work with Dr. Danilov was accepted to Blood Cancer Journal. Canping, a first-year PhD student, is a co-author of this paper. Cheers!
• 11/2022 Very lucky to have our resubmitted R01 scored at 7%. We are grateful for the encouragement, suggestions, and comments pointing out what we missed. Thank you, "ROSHAMBO"!
• 09/2022 Ya-Mei was awarded a T90 postdoc fellowship! Cheers!
• 08/2022 Guan and Ya-Mei's paper about Enzalutamide induced lineage plasticity with Alumkal lab was accepted to Nature Communications! Cheers!
• 08/2022 A collaborative work with Dr. Mara Sherman was accepted to Cancer Discovery! Congratulations!
• 04/2022 Guan and Chaojie's first author Nature paper was highlighted by Nature Reviews Cancer and Cancer Discovery!
• 03/2022 Guan and Chaojie's first author paper was published in Nature! A multidisciplinary collaboration with Moran Lab to study the novel roles of androgen receptor activity on resistance to T cell-targeted immunotherapy! CONGRATULATIONS to the Team!!
• 10/2021 Our collaborative paper with Schedin lab was accepted to PNAS!
• 09/2021 A collaborative paper was accepted to Cancer Discovery!
• 08/2021 Duanchen's bioinformatics method SCISSOR for phenotype-guided cell subpopulation identification from single-cell data was accepted to Nature Biotechnology! Congratulations!
• 08/2021 Ya-Mei joined our lab as a Postdoctoral Researcher. Welcome!
• 08/2021 Duanchen and Wes's study about young women's breast cancer was accepted to Nature Communications. Cheers!
• 05/2021 Duanchen's paper about blocking prostate cancer lineage plasticity through BET Bromodomain inhibition was accepted to Clinical Cancer Research! Congratulations!
• 02/2021 A new grant was awarded to the Xia Lab: Established Investigator Idea Development Award from the Department of Defense Prostate Cancer Research Program!
• 11/2020 Our collaboration with Dr. Alexey Danilov was funded by an R01 (scored at 2%) to study the mechanisms underlying the drug resistance in Mantle cell lymphoma!
• 09/2020 Guan has accepted the offer from Genentech as an associate scientist in Bioinformatics. Good experimental biologists have the intrinsic properties to become good computational biologists!
• 08/2020 A collaborative R01 with Dr. Alumkal was funded (scored at 2%). We are looking forward to working with Alumkal lab to target prostate cancer lineage plasticity!
• 06/2020 Guan's paper about copy number loss in enzalutamide-resistant prostate cancer was accepted to Clinical Cancer Research! Congratulations!
• 04/2020 Our paper about enzalutamide-resistant prostate cancer was accepted by PNAS!
• 03/2020 Guan received a travel award to present at the Thirteenth Annual Prostate Cancer Program Retreat in Florida.
• 02/2020 Our collaborative work in single-cell RNA-seq data analysis of tendon cells was published in eLife!
• 11/2019 Our paper is accepted to BMC Medical Genomics. Congratulations!
• 11/2019 Our research is funded by the Medical Research Foundation of Oregon!
• 08/2019 We are awarded a NIH R21 grant to study the alternative polyadenylation in immune cells. Congratulations!
• 05/2019 Guan's poster was selected into the discussion session at ASCO. Great job!
• 02/2019 Chaojie has obtained his dream job at Bristol-Myers Squibb as a bioinformatics scientist in cancer immunotherapy research. Good luck!
• 12/2018 We receive a CEDAR seed grant with Dr. Munks to study the earliest events in the failure of tumor-reactive T cells.
• 10/2018 We are awarded a Collins Medical Trust grant!
• 08/2018 Welcome to our new lab member Dr. Xiangnan Guan from Ohio State University.
• 08/2018 Xia lab moves into the new Knight Cancer Research Building which brings multidisciplinary scientists together under one roof to accelerate collaborations.
• 05/2018 Zheng is awarded a NIH career development grant! Congratulations!
• 03/2018 We are awarded a grant from the Childhood Leukemia Foundation!
• 01/2018 A Knight CEDAR grant is funded. We will work with Drs. Rozanov and Thompson for early breast cancer detection using TCR sequencing.
• 01/2018 The paper with Adey Lab is accepted to Nature Biotechnology. Duanchen and Zheng are co-authors and contributed to the nonnegative matrix factorization based clustering for the single-cell DNA methylation data.
• 01/2018 A manuscript is accepted to Nature Genetics. Zheng is a co-author.
• 10/2017 Dr. Chaojie Wang from Ohio State University joins our team. Chaojie majored in Biochemistry. Welcome!
• 09/2017 A manuscript is accepted to eLife. Zheng is a co-author.
• 07/2017 Welcome to new Postdoctoral Researcher Duanchen Sun, who joined the group after receiving his PhD in Operations Research and Bioinformatics from Chinese Academy of Sciences.
• 07/2017 Wes Horton joins the team as a Computational Biologist to provide bioinformatics support for our collaborators. Wes graduated from University of Oregon.
• 05/2017 A manuscript is accepted to PLoS Genet. Zheng is a co-author.
• 02/2017 A manuscript is accepted to Nucleic Acids Research. Zheng is a co-author.
• 12/2016 A manuscript is accepted to Scientific Reports. Zheng is a co-author.
• 11/2016 A manuscript is accepted to Science Advances. Zheng is a co-author.

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